Ebook Protein Crystallography: A Concise Guide, by Eaton E. Lattman, Patrick J. Loll
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Protein Crystallography: A Concise Guide, by Eaton E. Lattman, Patrick J. Loll
Ebook Protein Crystallography: A Concise Guide, by Eaton E. Lattman, Patrick J. Loll
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The proteome remains a mysterious realm. Researchers have determined the structures of only a small fraction of the proteins encoded by the human genome. Crystallography continues to be the primary method used to determine the structures of the remaining unknown proteins. This imaging technique uses the diffraction of X-rays to determine a protein’s three-dimensional molecular structure.
Drawing on years of research and teaching experience, Eaton E. Lattman and Patrick J. Loll use clear examples and abundant illustrations to provide a concise and accessible primer on protein crystallography. Discussing the basics of diffraction, the behavior of two- and three-dimensional crystals, phase determination (including MIR and MAD phasing and molecular replacement), the Patterson function, and refinement, Lattman and Loll provide a complete overview of this important technique, illuminated by physical insights.
The crisp writing style and simple illustrations will provide beginner crystallographers with a guide to the process of unraveling protein structure.
- Sales Rank: #2068517 in Books
- Brand: Brand: Johns Hopkins University Press
- Published on: 2008-03-26
- Original language: English
- Number of items: 1
- Dimensions: 9.00" h x .38" w x 6.00" l, .49 pounds
- Binding: Paperback
- 152 pages
- Used Book in Good Condition
Review
A useful source.
(Choice)It is gratifying to see such a nice piece of work and the book is highly recommended.
(Eddie Snell Reflexions: Newsletter of the American Crystallographic Association)One of the main assets of the book is its many illustrations. Without exception the figures are straightforward to interpret, and the visual support enables the newcomers to the field to follow the presented material easily.
(Linda Schuldt and Manfred S. Weiss Crystallography Reviews) About the Author
Eaton E. Lattman is chair of the Department of Biophysics at the Johns Hopkins University and editor-in-chief of the journal Proteins: Structure, Function, and Genetics. Patrick J. Loll is the director of the Biochemistry Graduate Program at Drexel University College of Medicine.
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